Grant Alerts
Selected Grants & Analysis are below. This a just a representative sample, contact us with your specific needs.
| Grant Name | Agency | Deadline | Award Amounts | Total Funding | Description |
|---|---|---|---|---|---|
| 2025 Port Infrastructure Development Program | USDOT | 30-Apr-25 | $112,500,000 | $450,000,000 | Support efforts by ports and industry stakeholders to improve port and related freight infrastructure to meet the nation’s freight transportation needs and ensure our port infrastructure can meet anticipated growth in freight volumes. Provides funding to ports in both urban and rural areas for planning and capital projects. Includes a statutory set-aside for small ports to continue to improve and expand their capacity to move freight reliably and efficiently and support local and regional economies. |
| Port Infrastructure Development Program | USDOT | 30-Apr-25 | $112,500,000 | $450,000,000 | Assists in funding eligible projects for the purpose of improving the safety, efficiency, or reliability of the movement of goods through ports and intermodal connections to ports. |
| National Human Trafficking Hotline (NHTH) | HHS | 2-May-25 | $5,000,000 | $5,000,000 | Funding for a national toll-free hotline that operates 24 hours a day, every day of the year via telephone, text, and chat, to assist adults and minors who have experienced a severe form of human trafficking. |
| Limited Competition: Clinical Research Sites (CRS) for the MACS/WIHS Combined Cohort Study (MWCCS) (U01 Clinical Trial Not Allowed) | HHS | 2-May-25 | $2,400,000 | Renews the MACS/WIHS Combined Cohort Study of HIV in United States Adults (MWCCS) for a 6-year project period (2026-2032). This NOFO is limited to institutions of higher education who were funded under RFA-HL-19-008 and will fund up to 13 Clinical Research Sites (CRS) for the MWCCS. | |
| Limited Competition: Data Analysis and Sharing Center (DASC) for the MACS/WIHS Combined Cohort Study (MWCCS) (U01 Clinical Trials Not Allowed) | HHS | 2-May-25 | $2,000,000 | $2,000,000 | Renews the MACS/WIHS Combined Cohort Study of HIV in United States Adults (MWCCS) for a 6-year project period (2026-2032). |
| Solar with Wildlife and Ecosystem Benefits 2 (SolWEB2) | DOE | 2-May-25 | $3,000,000 | $11,000,000 | Soliciting projects that will a) test strategies that mitigate adverse impacts and/or maximize benefits to wildlife and ecosystems, b) provide technical assistance and stakeholder engagement opportunities to facilitate strategies that improve the compatibility of LSS facilities with wildlife, or c) provide technical assistance and conduct outreach to facilitate the adoption of agrivoltaics. |
| Translational Bioinformatics and Experimental Approaches to Advance Drug Repositioning and Combination Therapy Development for Alzheimers Disease and Related Dementias (R01 Clinical Trial Not Allowed) | HHS | 7-May-25 | $1,000,000 | $1,000,000 | Seeking applications that propose to use mouse models to conduct rigorous preclinical testing of drugs or drug combinations currently used for other conditions, as well as investigational drugs at various stages of clinical development, predicted to be efficacious in AD/ADRD. |
| Agriculture and Food Research Initiative Sustainable Agricultural Systems | USDA | 15-May-25 | $10,000,000 | $70,000,000 | Seeks creative and visionary applications that take a systems approach for projects are expected to significantly improve the supply of affordable, safe, nutritious, and accessible agricultural products, while fostering economic development and rural prosperity in America. |
| Maximizing Algal System Yield (MASY) | DOE | 15-May-25 | $3,500,000 | $10,000,000 | Supports high-impact, applied R&D focused on relieving ‘pinch points’ in algal system cultivation and preprocessing, with the goal of improving process economics for biofuels and/or bioproducts. |
| Fiscal Year 2025 Solar Module and Solar Hardware (SMASH) Incubator | DOE | 30-May-25 | $4,000,000 | $20,000,000 | SMASH Incubator seeks to address the lack of sufficient private investment that is available to successfully commercialize the output of research, development, and demonstration activities and bring innovative solar photovoltaic (PV) technology to market. |
| Sustainable Propane and Renewable Chemicals (SPARC) | DOE | 30-May-25 | $2,500,000 | $23,000,000 | Supports research and development of domestic chemicals and fuels from a variety of biomass and waste resources. Concept Paper due date for this FOA is 3/14/2025. |
| Pilot-scale Rapid Operational Validation of key Energy Infrastructure Technologies (PROVE IT) - OCED Small Business Innovation Research (SBIR) | DOE | 2-Jun-25 | $22,000,000 | $31,000,000 | Supports the validation of existing pilot projects or subsystems in a relevant industrial environment to: 1) increase their technology readiness to the point of being able to be integrated in a large clean energy infrastructure project and 2) increase their adoption readiness level to medium/high. Up to $22 million for up to five pilot-scale-ready carbon capture projects. Up to $9 million for up to two long-duration energy storage projects. Pre-Application Submission Deadline: 4/7/2025 |
| Asthma and Allergic Diseases Cooperative Research Centers (U19 Clinical Trial Optional) | HHS | 13-Jun-25 | $1,400,000 | $6,000,000 | Invites applications from single institutions or consortia of institutions to participate in the Asthma and Allergic Diseases Cooperative Research Centers (AADCRC) program. |
| Vehicle Technology Office Program Wide | DOE | 18-Jun-25 | $6,000,000 | $88,000,000 | Seeking innovative solutions for on- and off-road vehicles in the areas of improved battery technology for both light- and heavy-duty applications, smart charging infrastructure, sustainable farming, workforce development, and demonstration and deployment of these new technologies. |
| Carbon Capture Demonstration Projects Program | DOE | 1-Jul-25 | $400,000,000 | Funding for integrated carbon capture, utilization, and storage (CCUS) projects that demonstrate substantial improvements in the efficiency, effectiveness, cost, and environmental performance of carbon capture technologies for power, industrial, and other commercial applications. | |
| Point Source Carbon Capture Large-Scale Pilots, Commercial Demonstrations, and Networked Demonstration Commercialization | DOE | 1-Jul-25 | $1,300,000 | $1,300,000,000 | Concept Paper Submission Deadline: 3/1/2025. Funding for integrated carbon capture, utilization, and storage (CCUS) projects that demonstrate substantial improvements in the efficiency, effectiveness, cost, and environmental performance of carbon capture technologies for power, industrial, and other commercial applications. Maximum Federal cost shares ranging from 50% to 80%. |
| The Circular Supply Chains Accelerator | DOE | 18-Jul-25 | $12,500,000 | $12,500,000 | Aims to promote innovative solutions for creating robust, sustainable, and efficient supply chains for critical materials needed for next-generation technologies. |
| Regional Direct Air Capture Hubs - Recurring Program | DOE | 31-Jul-25 | $1,400,000,000 | Deadlines for both Concept Papers and Pre-Applications are due by January 31, 2025. The program seeks to provide flexible and comprehensive pathways to spur the development of commercial DAC facilities, including DAC facilities at mid- to large-scale along with supporting infrastructure, and expand to Regional DAC Hubs. | |
| Bridge Investment Program - Large Bridge (2026 Funding) | USDOT | 1-Aug-25 | Rolling application for Large Bridge Project grants (a project with total eligible costs greater than $100 million) for awards under the Bridge Investment Program (BIP). | ||
| Development of Medications to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional) | HHS | 11-Aug-25 | $3,000,000 | Support the discovery and development of medications to prevent and treat substance use disorders (SUDs) and overdose. The UG3/UH3 Phase Innovation Awards Cooperative Agreement involves 2 phases. The UG3 is to support a project with specific milestones to be accomplished by the end of the 2-year period. The UH3 is to provide funding for 3 years to a project that successfully completed the milestones set in the UG3. | |
| Medications Development for Substance-Use Disorders (U01 Clinical Trial Optional) | HHS | 11-Aug-25 | $5,000,000 | Funding to accelerate the development of medication for the treatment of Substance Use Disorders (SUDs) by encouraging research applications to support a diverse array of preclinical and/or clinical research projects. It is expected that these U01s will be short-term (funded for up to 3 years) and large (up to $5 million per year) cooperative agreements with close monitoring and significant scientific involvement of NIDA staff. | |
| Energy Improvements in Rural or Remote Areas – Fiscal Year 2025 Release | DOE | 28-Aug-25 | $50,000,000 | $400,000,000 | Supports innovative, community-focused,?clean energy solutions for rural and remote communities of 10,000 people or few. Funding will?help rural and remote communities demonstrate replicable projects, ultimately encouraging widespread adoption and helping to lower energy costs, support local economic development, and enhance energy resiliency. |
| Continuum of Care Competition and Renewal or Replacement of Youth Homeless Demonstration Program Grants | HUD | 29-Aug-25 | $15,000,000 | $3,524,000,000 | Designed to promote a community-wide commitment to the goal of ending homelessness; to provide funding for efforts to quickly re-house homeless individuals, families, persons fleeing domestic violence, and youth while minimizing the trauma and dislocation caused by homelessness; to promote access to and effective utilization of mainstream programs by homeless; and to optimize self-sufficiency among those experiencing homelessness. |
| Building Biomedical Engineering Education, Research, and Innovation at Historically Black Colleges and Universities (HBCU eBETA) (UG3/UH3 Clinical Trial Not Allowed) | HHS | 30-Sep-25 | $1,000,000 | $2,400,000 | Provides funding to strengthen the research capacity and technology innovation at HBCUs, accelerate technology development and implementation, and prepare students at HBCUs for careers in biomedical engineering, imaging, and technology (BEIT). |
| Bridge Investment Program - Planning and Bridge Project Grants (2026 Funding) | USDOT | 1-Oct-25 | Rolling application for two funding categories: (1) Planning and (2) Bridge Project grants (a project with total eligible costs not greater than $100 million) for awards under the Bridge Investment Program (BIP). Planning application due 10/1/25 and bridge project application due 11/1/25. | ||
| Notice of Intent to Issue Fiscal Year 2025 Solar Module and Solar Hardware (SMASH) | DOE | 10-Oct-25 | Notice of Intent to Fund: The NOFO will seek to address the lack of sufficient private investment that is available to successfully commercialize research and development (R&D) and research, development, and demonstration (RD&D) activities and bring innovative solar photovoltaic (PV) technology to market. | ||
| Addressing Barriers to Healthcare Transitions for Survivors of Childhood and Adolescent Cancers (R01 Clinical Trial Optional) | HHS | 17-Oct-25 | $1,000,000 | $12,000,000 | Supports multi-level intervention studies that address individual and system level barriers to transitions from pediatric to adult care for survivors of childhood and adolescent cancers. NCI intends to commit $10 million total in FY 2025 and FY 2026 to fund up to 12 awards, across the prior and current issuance of this NOFO. |
| Bidirectional Influences Between Adolescent Social Media Use and Mental Health (R01 Clinical Trial Optional) | HHS | 20-Oct-25 | $1,000,000 | $5,000,000 | Seeking applications that focus on understanding bidirectional relationships between social media use and adolescent mental illness, psychiatric symptoms, and risk or resilience for psychopathology, as well as social media as a platform for facilitating the identification of adolescents with or at risk for mental illness, for encouraging appropriate mental health service use, and for delivering preventive and therapeutic interventions. |
| Bidirectional Influences Between Adolescent Social Media Use and Mental Health (R21 Clinical Trial Optional) | HHS | 20-Oct-25 | $1,000,000 | $5,000,000 | Seeking applications that focus on understanding bidirectional relationships between social media use and adolescent mental illness, psychiatric symptoms, and risk or resilience for psychopathology, as well as intervention/services research focused on examining the feasibility, acceptability, and preliminary utility of social-media focused interventions and services. |
| Contraceptive Development Research Centers (P50 Clinical Trial Optional) | HHS | 12-Nov-25 | $2,000,000 | $6,000,000 | Funding to support and facilitate multidisciplinary approaches towards the development of new and/or improved contraceptive methods for both men and women through the formation of a Contraceptive Development Research Center. |
| Agriculture and Food Research Initiative Competitive Grants Program Foundational and Applied Science Program | USDA | 31-Dec-25 | $15,000,000 | $300,000,000 | Funding to advance knowledge in both fundamental and applied sciences important to agriculture. Six priority areas: Plant Health and Production and Plant Products; Animal Health and Production and Animal Products; Food Safety, Nutrition, and Health; Bioenergy, Natural Resources, and Environment; Agriculture Systems and Technology; and Agriculture Economics and Rural Communities. |
| Carbon Dioxide Transportation Infrastructure Finance and Innovation Future Growth Grants | DOE | 2-Jan-26 | $500,000,000 | $500,000,000 | Provides financial assistance for designing, developing, and building CO2 transport systems whose capacity exceeds the CO2 volumes currently under commercial contract. |
| Collaborative Research Using Biosamples and/or Data from Type 1 Diabetes Clinical Studies (R01 - Clinical Trial Not Allowed) | HHS | 8-Mar-26 | $1,200,000 | This opportunity is intended to fund investigative teams collaborating to answer important questions about disease mechanisms leading to improved prevention of type 1 diabetes. | |
| HIV Prevention and Alcohol (R01 Clinical Trials Optional) | HHS | 7-May-26 | $1,000,000 | $2,000,000 | The NOFO seeks to expand the HIV/AIDS prevention toolkit among alcohol impacted populations with a range of patterns of episodic and long-term use and associated behavioral and biological risks for HIV acquisition. |
| Accelerated Innovation Deployment (AID) Demonstration | USDOT | 26-May-26 | $1,000,000 | FY 23-26 grant cycles. Funding to assistance under title 23, U.S.C. in any phase of a highway transportation project between project planning and project delivery, including planning, financing, operation, structures, materials, pavements, environment, and construction | |
| Standardizing Data and Metadata from Wearable Devices | HHS | 10-Jun-26 | Supports the creation of standards and related efforts that will allow researchers to easily access data from personal tracking devices. The awardees will be expected to partner with device manufacturers as well as the researcher community. Application budgets are not limited but need to reflect the actual needs of the proposed project. | ||
| REsearch Across Complementary and Integrative Health Institutions (REACH) Virtual Resource Centers | HHS | 15-Aug-26 | $850,000 | $2,750,000 | REACH virtual resource centers will foster institutional partnerships and provide resources to support research activities and research training for faculty who work at accredited complementary and integrative health clinical institutions. |
| Institutional Training Programs to Advance Translational Research on Alzheimer's Disease (AD) and AD-Related Dementias (ADRD) (T32 Clinical Trial Not Allowed) | HHS | 25-Sep-26 | $900,000 | $2,700,000 | This NOFO will support institutional training programs for predoctoral and postdoctoral level researchers with diverse educational backgrounds (i.e., basic biology, translational and clinical research, data science). |
| BRAIN Initiative: Clinical Studies to Advance Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UH3 Clinical Trial Optional) | HHS | 28-Sep-26 | $2,000,000 | $10,000,000 | Funding to encourage investigators to pursue a small clinical trial to obtain critical information necessary to advance recording and/or stimulating devices to treat central nervous system disorders and better understand the human brain (e.g., Early Feasibility Study). |
| BRAIN Initiative: Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UG3/UH3 Clinical Trial Optional) | HHS | 28-Sep-26 | $2,000,000 | $10,000,000 | Funding to encourage investigators to pursue translational activities and small clinical studies for recording and/or stimulating devices to treat central nervous system disorders and better understand the human brain. |
| Environmental Health Sciences Core Centers Program (P30 Clinical Trials Optional) | HHS | 29-Jan-27 | $1,500,000 | $6,000,000 | Seeking applications for Environmental Health Sciences Core Centers (EHSCC), expected to be the thought leaders for the field and advance the goals of the 2025-2029 NIEHS Strategic Plan. |
| BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed) | HHS | 8-Feb-27 | $1,300,000 | $8,000,000 | Seeking applications that will develop and validate novel tools to facilitate the detailed analysis of complex circuits and provide insights into cellular interactions that underlie brain function. |
| High Priority HIV and Substance Use Research (R01 Clinical Trial Optional) | HHS | 11-Feb-27 | $3,000,000 | Invites innovative research projects with the potential to open new areas of HIV/AIDS research and/or lead to new avenues for prevention, treatment and cure of HIV among people who use drugs (PWUD). | |
| High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed) | HHS | 1-Jun-27 | $2,000,000 | Seeking applications from groups of NIH-supported investigators to purchase or upgrade a single item of high-end, specialized, commercially available instruments or integrated systems. | |
| Reissue PAR-21-233 - The Blueprint Neurotherapeutics Network for Biologics (BPN-Biologics) | HHS | 8-Aug-27 | $200,000,000 | Provides support for biologic-based therapeutic discovery and development, from lead optimization through phase I clinical testing. | |
| Alzheimer's Drug-Development Program (U01 Clinical Trial Optional) | HHS | 5-Nov-27 | $1,500,000 | Funding support for the pre-clinical and early stage clinical (Phase I) development of novel small-molecule and biologic drug candidates that prevent Alzheimer's disease (AD), slow its progression, or treat its cognitive and behavioral symptoms. | |
| Leveraging Network Infrastructure to Conduct Innovative Research for Women, Children, Pregnant and Lactating Individuals, and Persons with Disabilities (UG3/UH3 - Clinical Trial Optional) | HHS | 15-Nov-27 | $6,250,000 | Leverages NICHD clinical research Network infrastructure relevant to infants, children, women, pregnant and lactating individuals, and persons with disabilities to conduct innovative, multisite, investigator-initiated clinical trials and observational studies. | |
| Leveraging Network Infrastructure to Conduct Innovative Research for Women, Children, Pregnant and Lactating Individuals, and Persons with Disabilities (UG3/UH3 - Clinical Trial Optional) | HHS | 15-Nov-27 | $6,250,000 | $6,250,000 | Funding to leverage NICHD clinical research Network infrastructure relevant to infants, children, women, pregnant and lactating individuals, and persons with disabilities to conduct innovative, multisite, investigator-initiated clinical trials and observational studies. |
| Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed) | HHS | 3-Dec-27 | $1,000,000 | $2,000,000 | Invites applications proposing the innovative analysis of existing social science, behavioral, administrative, and neuroimaging data to study the etiology and epidemiology of drug using behaviors and related disorders, prevention of drug use and HIV, and health service utilization. |
| Laboratory Flexible Funding Model (LFFM) | HHS | 11-Jan-28 | $1,500,000 | This cooperative agreement is intended to enhance the capacity and capabilities of state human and animal food testing laboratories in support of an integrated food safety system (IFSS). | |
| Animal and Veterinary Innovation Centers | HHS | 8-May-28 | $1,250,000 | $3,000,000 | Soliciting applications for inclusion as Animal and Veterinary Innovation Centers, which are intended to form long-term partnerships to address priority areas for FDA's Center for Veterinary Medicine (CVM). |
| Seeding Critical Advances for Leading Energy technologies with Untapped Potential (SCALEUP) Ready program | DOE | 29-Sep-29 | $200,000,000 | Provides a vital mechanism for the support of innovative energy R&D that complements ARPA-E’s primary R&D focus on early-stage transformational energy technologies that still require proof-of-concept. | |
| NOI: Regional Direct Air Capture Hubs – Recurring Program | DOE | $1,300,000,000 | Notice of Intent to Issue Notice of Funding Opportunity: Regional Direct Air Capture Hubs – Recurring Program to support the commercialization of direct air capture (DAC) solutions and the development of four regional DAC hubs. | ||
| NOI Renewable Integration Management with Innovative High Voltage Direct Current Power Circuit Breakers (REIMAGINE BREAKERS) | DOE | $8,000,000 | Notice of Intent to Fund: Program funding to improve risk assessment and communication for grid operators in the age of big data. | ||
| NOI to Issue Bipartisan Infrastructure Law: Funding Opportunity Announcement No. DE-FOA-0003434 | DOE | Notice of Intent (NOI) to issue an Funding Opportunity Annoucement (FOA) entitled Electric Drive Vehicle Battery Improving Economics, Recovery and Reuse, and State of Health to support research, development, and demonstration of: 1) second-life applications for electric drive vehicle batteries that have been used to power electric drive vehicles; and 2) technologies and processes for final recycling and disposal of the [electric drive vehicle batteries]. | |||
| NOI to release Energy Improvements in Rural or Remote Areas FY24 | DOE | Notice of Intent (NOI) to issue a NOFO entitled “Energy Improvements in Rural or Remote Areas FY24”. The goals are to deliver measurable and sustained benefits to people who live in rural or remote areas; demonstrate rural or remote energy system approaches; and build clean energy knowledge, capacity, and self-reliance in rural and remote parts of America. | |||
| NOI to release Regional Direct Air Capture Hubs – Recurring Program | DOE | Notice of Intent (NOI) to issue a Notice of Funding Opportunity (NOFO) entitled “Regional Direct Air Capture Hubs – Recurring Program” in the fourth quarter of 2024. The goal of this NOFO, along with potential subsequent re-openings and related solicitations (collectively, “the Program”), is to support the commercialization of direct air capture (DAC) solutions and the development of four regional DAC hubs. | |||
| Notice of Intent to Issue FOA number DE-FOA-0003383 entitled Fiscal Year 2024 Vehicle Technologies Office Batteries & Electrification FOA | DOE | Forecasted Opportunity for July/August 2024. The potential funding will drive innovations in low-cost electric vehicle (EV) battery manufacturing, using inexpensive and abundant battery materials in support of a viable domestic materials supply chain, and conducting smart-charge management demonstrations. | |||
| Notice of Intent to Issue: Energy Storage Pilot Demonstrations | DOE | $20,000,000 | $100,000,000 | Anticipated release late summer/early fall. Will support pilot-scale demonstrations for non-lithium, long duration energy storage solutions that advance technical maturity, reduce uncertainty in cost and performance characteristics, generate operational datasets, and increase investor and end-user confidence in technical and commercial maturation pathways and timelines. |
Grant Alerts
Selected Grants & Analysis are below. This a just a representative sample, contact us with your specific needs.
| Grant Name | Agency | Deadline | Award Amounts | Total Funding | Description |
|---|---|---|---|---|---|
| 2025 Port Infrastructure Development Program | USDOT | 30-Apr-25 | $112,500,000 | $450,000,000 | Support efforts by ports and industry stakeholders to improve port and related freight infrastructure to meet the nation’s freight transportation needs and ensure our port infrastructure can meet anticipated growth in freight volumes. Provides funding to ports in both urban and rural areas for planning and capital projects. Includes a statutory set-aside for small ports to continue to improve and expand their capacity to move freight reliably and efficiently and support local and regional economies. |
| Port Infrastructure Development Program | USDOT | 30-Apr-25 | $112,500,000 | $450,000,000 | Assists in funding eligible projects for the purpose of improving the safety, efficiency, or reliability of the movement of goods through ports and intermodal connections to ports. |
| National Human Trafficking Hotline (NHTH) | HHS | 2-May-25 | $5,000,000 | $5,000,000 | Funding for a national toll-free hotline that operates 24 hours a day, every day of the year via telephone, text, and chat, to assist adults and minors who have experienced a severe form of human trafficking. |
| Limited Competition: Clinical Research Sites (CRS) for the MACS/WIHS Combined Cohort Study (MWCCS) (U01 Clinical Trial Not Allowed) | HHS | 2-May-25 | $2,400,000 | Renews the MACS/WIHS Combined Cohort Study of HIV in United States Adults (MWCCS) for a 6-year project period (2026-2032). This NOFO is limited to institutions of higher education who were funded under RFA-HL-19-008 and will fund up to 13 Clinical Research Sites (CRS) for the MWCCS. | |
| Limited Competition: Data Analysis and Sharing Center (DASC) for the MACS/WIHS Combined Cohort Study (MWCCS) (U01 Clinical Trials Not Allowed) | HHS | 2-May-25 | $2,000,000 | $2,000,000 | Renews the MACS/WIHS Combined Cohort Study of HIV in United States Adults (MWCCS) for a 6-year project period (2026-2032). |
| Solar with Wildlife and Ecosystem Benefits 2 (SolWEB2) | DOE | 2-May-25 | $3,000,000 | $11,000,000 | Soliciting projects that will a) test strategies that mitigate adverse impacts and/or maximize benefits to wildlife and ecosystems, b) provide technical assistance and stakeholder engagement opportunities to facilitate strategies that improve the compatibility of LSS facilities with wildlife, or c) provide technical assistance and conduct outreach to facilitate the adoption of agrivoltaics. |
| Translational Bioinformatics and Experimental Approaches to Advance Drug Repositioning and Combination Therapy Development for Alzheimers Disease and Related Dementias (R01 Clinical Trial Not Allowed) | HHS | 7-May-25 | $1,000,000 | $1,000,000 | Seeking applications that propose to use mouse models to conduct rigorous preclinical testing of drugs or drug combinations currently used for other conditions, as well as investigational drugs at various stages of clinical development, predicted to be efficacious in AD/ADRD. |
| Agriculture and Food Research Initiative Sustainable Agricultural Systems | USDA | 15-May-25 | $10,000,000 | $70,000,000 | Seeks creative and visionary applications that take a systems approach for projects are expected to significantly improve the supply of affordable, safe, nutritious, and accessible agricultural products, while fostering economic development and rural prosperity in America. |
| Maximizing Algal System Yield (MASY) | DOE | 15-May-25 | $3,500,000 | $10,000,000 | Supports high-impact, applied R&D focused on relieving ‘pinch points’ in algal system cultivation and preprocessing, with the goal of improving process economics for biofuels and/or bioproducts. |
| Fiscal Year 2025 Solar Module and Solar Hardware (SMASH) Incubator | DOE | 30-May-25 | $4,000,000 | $20,000,000 | SMASH Incubator seeks to address the lack of sufficient private investment that is available to successfully commercialize the output of research, development, and demonstration activities and bring innovative solar photovoltaic (PV) technology to market. |
| Sustainable Propane and Renewable Chemicals (SPARC) | DOE | 30-May-25 | $2,500,000 | $23,000,000 | Supports research and development of domestic chemicals and fuels from a variety of biomass and waste resources. Concept Paper due date for this FOA is 3/14/2025. |
| Pilot-scale Rapid Operational Validation of key Energy Infrastructure Technologies (PROVE IT) - OCED Small Business Innovation Research (SBIR) | DOE | 2-Jun-25 | $22,000,000 | $31,000,000 | Supports the validation of existing pilot projects or subsystems in a relevant industrial environment to: 1) increase their technology readiness to the point of being able to be integrated in a large clean energy infrastructure project and 2) increase their adoption readiness level to medium/high. Up to $22 million for up to five pilot-scale-ready carbon capture projects. Up to $9 million for up to two long-duration energy storage projects. Pre-Application Submission Deadline: 4/7/2025 |
| Asthma and Allergic Diseases Cooperative Research Centers (U19 Clinical Trial Optional) | HHS | 13-Jun-25 | $1,400,000 | $6,000,000 | Invites applications from single institutions or consortia of institutions to participate in the Asthma and Allergic Diseases Cooperative Research Centers (AADCRC) program. |
| Vehicle Technology Office Program Wide | DOE | 18-Jun-25 | $6,000,000 | $88,000,000 | Seeking innovative solutions for on- and off-road vehicles in the areas of improved battery technology for both light- and heavy-duty applications, smart charging infrastructure, sustainable farming, workforce development, and demonstration and deployment of these new technologies. |
| Carbon Capture Demonstration Projects Program | DOE | 1-Jul-25 | $400,000,000 | Funding for integrated carbon capture, utilization, and storage (CCUS) projects that demonstrate substantial improvements in the efficiency, effectiveness, cost, and environmental performance of carbon capture technologies for power, industrial, and other commercial applications. | |
| Point Source Carbon Capture Large-Scale Pilots, Commercial Demonstrations, and Networked Demonstration Commercialization | DOE | 1-Jul-25 | $1,300,000 | $1,300,000,000 | Concept Paper Submission Deadline: 3/1/2025. Funding for integrated carbon capture, utilization, and storage (CCUS) projects that demonstrate substantial improvements in the efficiency, effectiveness, cost, and environmental performance of carbon capture technologies for power, industrial, and other commercial applications. Maximum Federal cost shares ranging from 50% to 80%. |
| The Circular Supply Chains Accelerator | DOE | 18-Jul-25 | $12,500,000 | $12,500,000 | Aims to promote innovative solutions for creating robust, sustainable, and efficient supply chains for critical materials needed for next-generation technologies. |
| Regional Direct Air Capture Hubs - Recurring Program | DOE | 31-Jul-25 | $1,400,000,000 | Deadlines for both Concept Papers and Pre-Applications are due by January 31, 2025. The program seeks to provide flexible and comprehensive pathways to spur the development of commercial DAC facilities, including DAC facilities at mid- to large-scale along with supporting infrastructure, and expand to Regional DAC Hubs. | |
| Bridge Investment Program - Large Bridge (2026 Funding) | USDOT | 1-Aug-25 | Rolling application for Large Bridge Project grants (a project with total eligible costs greater than $100 million) for awards under the Bridge Investment Program (BIP). | ||
| Development of Medications to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional) | HHS | 11-Aug-25 | $3,000,000 | Support the discovery and development of medications to prevent and treat substance use disorders (SUDs) and overdose. The UG3/UH3 Phase Innovation Awards Cooperative Agreement involves 2 phases. The UG3 is to support a project with specific milestones to be accomplished by the end of the 2-year period. The UH3 is to provide funding for 3 years to a project that successfully completed the milestones set in the UG3. | |
| Medications Development for Substance-Use Disorders (U01 Clinical Trial Optional) | HHS | 11-Aug-25 | $5,000,000 | Funding to accelerate the development of medication for the treatment of Substance Use Disorders (SUDs) by encouraging research applications to support a diverse array of preclinical and/or clinical research projects. It is expected that these U01s will be short-term (funded for up to 3 years) and large (up to $5 million per year) cooperative agreements with close monitoring and significant scientific involvement of NIDA staff. | |
| Energy Improvements in Rural or Remote Areas – Fiscal Year 2025 Release | DOE | 28-Aug-25 | $50,000,000 | $400,000,000 | Supports innovative, community-focused,?clean energy solutions for rural and remote communities of 10,000 people or few. Funding will?help rural and remote communities demonstrate replicable projects, ultimately encouraging widespread adoption and helping to lower energy costs, support local economic development, and enhance energy resiliency. |
| Continuum of Care Competition and Renewal or Replacement of Youth Homeless Demonstration Program Grants | HUD | 29-Aug-25 | $15,000,000 | $3,524,000,000 | Designed to promote a community-wide commitment to the goal of ending homelessness; to provide funding for efforts to quickly re-house homeless individuals, families, persons fleeing domestic violence, and youth while minimizing the trauma and dislocation caused by homelessness; to promote access to and effective utilization of mainstream programs by homeless; and to optimize self-sufficiency among those experiencing homelessness. |
| Building Biomedical Engineering Education, Research, and Innovation at Historically Black Colleges and Universities (HBCU eBETA) (UG3/UH3 Clinical Trial Not Allowed) | HHS | 30-Sep-25 | $1,000,000 | $2,400,000 | Provides funding to strengthen the research capacity and technology innovation at HBCUs, accelerate technology development and implementation, and prepare students at HBCUs for careers in biomedical engineering, imaging, and technology (BEIT). |
| Bridge Investment Program - Planning and Bridge Project Grants (2026 Funding) | USDOT | 1-Oct-25 | Rolling application for two funding categories: (1) Planning and (2) Bridge Project grants (a project with total eligible costs not greater than $100 million) for awards under the Bridge Investment Program (BIP). Planning application due 10/1/25 and bridge project application due 11/1/25. | ||
| Notice of Intent to Issue Fiscal Year 2025 Solar Module and Solar Hardware (SMASH) | DOE | 10-Oct-25 | Notice of Intent to Fund: The NOFO will seek to address the lack of sufficient private investment that is available to successfully commercialize research and development (R&D) and research, development, and demonstration (RD&D) activities and bring innovative solar photovoltaic (PV) technology to market. | ||
| Addressing Barriers to Healthcare Transitions for Survivors of Childhood and Adolescent Cancers (R01 Clinical Trial Optional) | HHS | 17-Oct-25 | $1,000,000 | $12,000,000 | Supports multi-level intervention studies that address individual and system level barriers to transitions from pediatric to adult care for survivors of childhood and adolescent cancers. NCI intends to commit $10 million total in FY 2025 and FY 2026 to fund up to 12 awards, across the prior and current issuance of this NOFO. |
| Bidirectional Influences Between Adolescent Social Media Use and Mental Health (R01 Clinical Trial Optional) | HHS | 20-Oct-25 | $1,000,000 | $5,000,000 | Seeking applications that focus on understanding bidirectional relationships between social media use and adolescent mental illness, psychiatric symptoms, and risk or resilience for psychopathology, as well as social media as a platform for facilitating the identification of adolescents with or at risk for mental illness, for encouraging appropriate mental health service use, and for delivering preventive and therapeutic interventions. |
| Bidirectional Influences Between Adolescent Social Media Use and Mental Health (R21 Clinical Trial Optional) | HHS | 20-Oct-25 | $1,000,000 | $5,000,000 | Seeking applications that focus on understanding bidirectional relationships between social media use and adolescent mental illness, psychiatric symptoms, and risk or resilience for psychopathology, as well as intervention/services research focused on examining the feasibility, acceptability, and preliminary utility of social-media focused interventions and services. |
| Contraceptive Development Research Centers (P50 Clinical Trial Optional) | HHS | 12-Nov-25 | $2,000,000 | $6,000,000 | Funding to support and facilitate multidisciplinary approaches towards the development of new and/or improved contraceptive methods for both men and women through the formation of a Contraceptive Development Research Center. |
| Agriculture and Food Research Initiative Competitive Grants Program Foundational and Applied Science Program | USDA | 31-Dec-25 | $15,000,000 | $300,000,000 | Funding to advance knowledge in both fundamental and applied sciences important to agriculture. Six priority areas: Plant Health and Production and Plant Products; Animal Health and Production and Animal Products; Food Safety, Nutrition, and Health; Bioenergy, Natural Resources, and Environment; Agriculture Systems and Technology; and Agriculture Economics and Rural Communities. |
| Carbon Dioxide Transportation Infrastructure Finance and Innovation Future Growth Grants | DOE | 2-Jan-26 | $500,000,000 | $500,000,000 | Provides financial assistance for designing, developing, and building CO2 transport systems whose capacity exceeds the CO2 volumes currently under commercial contract. |
| Collaborative Research Using Biosamples and/or Data from Type 1 Diabetes Clinical Studies (R01 - Clinical Trial Not Allowed) | HHS | 8-Mar-26 | $1,200,000 | This opportunity is intended to fund investigative teams collaborating to answer important questions about disease mechanisms leading to improved prevention of type 1 diabetes. | |
| HIV Prevention and Alcohol (R01 Clinical Trials Optional) | HHS | 7-May-26 | $1,000,000 | $2,000,000 | The NOFO seeks to expand the HIV/AIDS prevention toolkit among alcohol impacted populations with a range of patterns of episodic and long-term use and associated behavioral and biological risks for HIV acquisition. |
| Accelerated Innovation Deployment (AID) Demonstration | USDOT | 26-May-26 | $1,000,000 | FY 23-26 grant cycles. Funding to assistance under title 23, U.S.C. in any phase of a highway transportation project between project planning and project delivery, including planning, financing, operation, structures, materials, pavements, environment, and construction | |
| Standardizing Data and Metadata from Wearable Devices | HHS | 10-Jun-26 | Supports the creation of standards and related efforts that will allow researchers to easily access data from personal tracking devices. The awardees will be expected to partner with device manufacturers as well as the researcher community. Application budgets are not limited but need to reflect the actual needs of the proposed project. | ||
| REsearch Across Complementary and Integrative Health Institutions (REACH) Virtual Resource Centers | HHS | 15-Aug-26 | $850,000 | $2,750,000 | REACH virtual resource centers will foster institutional partnerships and provide resources to support research activities and research training for faculty who work at accredited complementary and integrative health clinical institutions. |
| Institutional Training Programs to Advance Translational Research on Alzheimer's Disease (AD) and AD-Related Dementias (ADRD) (T32 Clinical Trial Not Allowed) | HHS | 25-Sep-26 | $900,000 | $2,700,000 | This NOFO will support institutional training programs for predoctoral and postdoctoral level researchers with diverse educational backgrounds (i.e., basic biology, translational and clinical research, data science). |
| BRAIN Initiative: Clinical Studies to Advance Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UH3 Clinical Trial Optional) | HHS | 28-Sep-26 | $2,000,000 | $10,000,000 | Funding to encourage investigators to pursue a small clinical trial to obtain critical information necessary to advance recording and/or stimulating devices to treat central nervous system disorders and better understand the human brain (e.g., Early Feasibility Study). |
| BRAIN Initiative: Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UG3/UH3 Clinical Trial Optional) | HHS | 28-Sep-26 | $2,000,000 | $10,000,000 | Funding to encourage investigators to pursue translational activities and small clinical studies for recording and/or stimulating devices to treat central nervous system disorders and better understand the human brain. |
| Environmental Health Sciences Core Centers Program (P30 Clinical Trials Optional) | HHS | 29-Jan-27 | $1,500,000 | $6,000,000 | Seeking applications for Environmental Health Sciences Core Centers (EHSCC), expected to be the thought leaders for the field and advance the goals of the 2025-2029 NIEHS Strategic Plan. |
| BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed) | HHS | 8-Feb-27 | $1,300,000 | $8,000,000 | Seeking applications that will develop and validate novel tools to facilitate the detailed analysis of complex circuits and provide insights into cellular interactions that underlie brain function. |
| High Priority HIV and Substance Use Research (R01 Clinical Trial Optional) | HHS | 11-Feb-27 | $3,000,000 | Invites innovative research projects with the potential to open new areas of HIV/AIDS research and/or lead to new avenues for prevention, treatment and cure of HIV among people who use drugs (PWUD). | |
| High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed) | HHS | 1-Jun-27 | $2,000,000 | Seeking applications from groups of NIH-supported investigators to purchase or upgrade a single item of high-end, specialized, commercially available instruments or integrated systems. | |
| Reissue PAR-21-233 - The Blueprint Neurotherapeutics Network for Biologics (BPN-Biologics) | HHS | 8-Aug-27 | $200,000,000 | Provides support for biologic-based therapeutic discovery and development, from lead optimization through phase I clinical testing. | |
| Alzheimer's Drug-Development Program (U01 Clinical Trial Optional) | HHS | 5-Nov-27 | $1,500,000 | Funding support for the pre-clinical and early stage clinical (Phase I) development of novel small-molecule and biologic drug candidates that prevent Alzheimer's disease (AD), slow its progression, or treat its cognitive and behavioral symptoms. | |
| Leveraging Network Infrastructure to Conduct Innovative Research for Women, Children, Pregnant and Lactating Individuals, and Persons with Disabilities (UG3/UH3 - Clinical Trial Optional) | HHS | 15-Nov-27 | $6,250,000 | Leverages NICHD clinical research Network infrastructure relevant to infants, children, women, pregnant and lactating individuals, and persons with disabilities to conduct innovative, multisite, investigator-initiated clinical trials and observational studies. | |
| Leveraging Network Infrastructure to Conduct Innovative Research for Women, Children, Pregnant and Lactating Individuals, and Persons with Disabilities (UG3/UH3 - Clinical Trial Optional) | HHS | 15-Nov-27 | $6,250,000 | $6,250,000 | Funding to leverage NICHD clinical research Network infrastructure relevant to infants, children, women, pregnant and lactating individuals, and persons with disabilities to conduct innovative, multisite, investigator-initiated clinical trials and observational studies. |
| Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed) | HHS | 3-Dec-27 | $1,000,000 | $2,000,000 | Invites applications proposing the innovative analysis of existing social science, behavioral, administrative, and neuroimaging data to study the etiology and epidemiology of drug using behaviors and related disorders, prevention of drug use and HIV, and health service utilization. |
| Laboratory Flexible Funding Model (LFFM) | HHS | 11-Jan-28 | $1,500,000 | This cooperative agreement is intended to enhance the capacity and capabilities of state human and animal food testing laboratories in support of an integrated food safety system (IFSS). | |
| Animal and Veterinary Innovation Centers | HHS | 8-May-28 | $1,250,000 | $3,000,000 | Soliciting applications for inclusion as Animal and Veterinary Innovation Centers, which are intended to form long-term partnerships to address priority areas for FDA's Center for Veterinary Medicine (CVM). |
| Seeding Critical Advances for Leading Energy technologies with Untapped Potential (SCALEUP) Ready program | DOE | 29-Sep-29 | $200,000,000 | Provides a vital mechanism for the support of innovative energy R&D that complements ARPA-E’s primary R&D focus on early-stage transformational energy technologies that still require proof-of-concept. | |
| NOI: Regional Direct Air Capture Hubs – Recurring Program | DOE | $1,300,000,000 | Notice of Intent to Issue Notice of Funding Opportunity: Regional Direct Air Capture Hubs – Recurring Program to support the commercialization of direct air capture (DAC) solutions and the development of four regional DAC hubs. | ||
| NOI Renewable Integration Management with Innovative High Voltage Direct Current Power Circuit Breakers (REIMAGINE BREAKERS) | DOE | $8,000,000 | Notice of Intent to Fund: Program funding to improve risk assessment and communication for grid operators in the age of big data. | ||
| NOI to Issue Bipartisan Infrastructure Law: Funding Opportunity Announcement No. DE-FOA-0003434 | DOE | Notice of Intent (NOI) to issue an Funding Opportunity Annoucement (FOA) entitled Electric Drive Vehicle Battery Improving Economics, Recovery and Reuse, and State of Health to support research, development, and demonstration of: 1) second-life applications for electric drive vehicle batteries that have been used to power electric drive vehicles; and 2) technologies and processes for final recycling and disposal of the [electric drive vehicle batteries]. | |||
| NOI to release Energy Improvements in Rural or Remote Areas FY24 | DOE | Notice of Intent (NOI) to issue a NOFO entitled “Energy Improvements in Rural or Remote Areas FY24”. The goals are to deliver measurable and sustained benefits to people who live in rural or remote areas; demonstrate rural or remote energy system approaches; and build clean energy knowledge, capacity, and self-reliance in rural and remote parts of America. | |||
| NOI to release Regional Direct Air Capture Hubs – Recurring Program | DOE | Notice of Intent (NOI) to issue a Notice of Funding Opportunity (NOFO) entitled “Regional Direct Air Capture Hubs – Recurring Program” in the fourth quarter of 2024. The goal of this NOFO, along with potential subsequent re-openings and related solicitations (collectively, “the Program”), is to support the commercialization of direct air capture (DAC) solutions and the development of four regional DAC hubs. | |||
| Notice of Intent to Issue FOA number DE-FOA-0003383 entitled Fiscal Year 2024 Vehicle Technologies Office Batteries & Electrification FOA | DOE | Forecasted Opportunity for July/August 2024. The potential funding will drive innovations in low-cost electric vehicle (EV) battery manufacturing, using inexpensive and abundant battery materials in support of a viable domestic materials supply chain, and conducting smart-charge management demonstrations. | |||
| Notice of Intent to Issue: Energy Storage Pilot Demonstrations | DOE | $20,000,000 | $100,000,000 | Anticipated release late summer/early fall. Will support pilot-scale demonstrations for non-lithium, long duration energy storage solutions that advance technical maturity, reduce uncertainty in cost and performance characteristics, generate operational datasets, and increase investor and end-user confidence in technical and commercial maturation pathways and timelines. |
