Grant Alerts
Selected Grants & Analysis are below. This a just a representative sample, contact us with your specific needs.
| Grant Name | Agency | Deadline | Award Amounts | Total Funding | Description |
|---|---|---|---|---|---|
| Cooperative Institute Fostering Aquaculture Research and Marketing (CIFARM) | DOC | 9/5/2025 | $300,000,000 | $300,000,000 | Supports the establishment of a Cooperative Institute Fostering Aquaculture Research and Marketing (CIFARM) that will advance key goals in aquaculture, fostering innovation, promote environmental stewardship, and build strong coastal economies; support the robust development of aquaculture in the United States to address the seafood import deficit and benefit the economy; and help the agency fulfill the tenets of the NOAA Aquaculture Strategic Plan. |
| Community College Initiative Program | DOS | 8/4/2025 | $3,937,500 | $3,937,500 | ECA is seeking proposal submissions for one cooperative agreement to design, implement, and oversee the Community College Initiative Program. |
| DoD Toxic Exposures Clinical Trial Partnership Award | DOD | 10/16/2025 | $4,200,000 | $4,200,000 | Funding to support new or existing collaborative partnerships that will rapidly implement clinical trials with the potential to have a significant impact on the prevention, treatment or management of symptoms, diseases, or conditions associated with or resulting from military-related toxic exposures. |
| DoD Toxic Exposures Translational Research Partnership Award | DOD | 10/16/2025 | $2,240,000 | $4,480,000 | Funding to support new or existing collaborative partnerships to pursue translational research that will accelerate the movement of promising ideas in military-related toxic exposure research into clinical applications, including health care products, interventions, technologies, and/or clinical practice guidelines. |
| DHA- Military Health System Research Program | DOD | 10/16/2025 | $1,000,000 | $10,000,000 | Funds innovative and groundbreaking research that examines factors that affect the military health enterprise in terms of economics/cost, quality, outcomes, variation, policies, and the impact to service member readiness. |
| DoD Prostate Cancer, Idea Development Award | DOD | 8/29/2025 | $7,200,000 | $30,500,000 | Supports new ideas that represent innovative approaches to prostate cancer research and have the potential to make an important contribution to the PCRP mission. |
| DoD Prostate Cancer, Clinical Consortium Award | DOD | 8/29/2025 | $7,600,000 | $32,500,000 | Provides support to develop, maintain, and enhance the necessary collaborations and resources to rapidly execute phase 2 and/or phase 2-linked phase 1 (phase1/2) prostate cancer clinical trials. Supports one coordinating center and multiple clinical research sites. |
| DOD Peer Reviewed Cancer, Clinical Trial Award | DOD | 9/25/2025 | $3,000,000 | $33,600,000 | Supports the rapid implementation of clinical trials with the potential to have a significant impact on the treatment or management of cancer within at least one of the FY25 PRCRP topic areas. Clinical trials may be designed to evaluate promising new products, pharmacologic agents (drugs or biologics), devices, clinical guidance, and/or emerging approaches and technologies. Proposed projects may range from small proof-of-concept trials that evaluate the effects of interventions or inform the design of more advanced trials to large-scale trials (up to phase III) to determine efficacy in relevant patient populations. |
| DoD Melanoma, Team Science Award | DOD | 10/1/2025 | $2,400,000 | $16,800,000 | Supports a broad range of hypothesis-driven, multidisciplinary studies that have a short-term goal of advancing the state of the science in melanoma research and/or patient care. |
| DoD Melanoma, Survivorship Research Award | DOD | 10/1/2025 | $1,160,000 | $2,320,000 | Addresses the relatively new and underfunded area of melanoma-specific survivorship by supporting a broad range of innovative and impactful research that has the intended outcome of improving the health and well-being of melanoma survivors, their families, and/or their caregivers. |
| DoD Melanoma, Focused Program Award – Rare Melanomas | DOD | 10/1/2025 | $3,200,000 | $6,400,000 | Supports a multidisciplinary research program of at least two, but not more than three, distinct but complementary research projects addressing an overarching question relevant to rare melanomas. |
| Regional Infrastructure Accelerator Program | USDOT | RIA grants assist entities in developing improved infrastructure priorities and financing strategies for the accelerated development of a project that is eligible for funding under the Transportation Infrastructure Finance and Innovation Act (TIFIA) Credit Program. Next round anticipated in Spring 2026. | |||
| DOD Duchenne Muscular Dystrophy, Clinical/Translational Research Award | DOD | 8/8/2025 | $1,712,000 | $8,560,000 | Supports advanced translational research that will accelerate the movement of promising ideas in Duchenne muscular dystrophy (DMD) research into clinical applications. |
| DoD Military Burn, Patient-Centered Research Award | DOD | 9/8/2025 | $1,700,000 | $3,400,000 | Seeks to bridge the gap between research, practice, and policy by developing a knowledge base that provides clinically useful findings about how interventions, clinical practices, guidelines, tools, and policies can be deployed to burn patients in an austere, resource-limited, distributed operational environment at the point of need. |
| DoD Military Burn, Technology/Therapeutic Development Award | DOD | 9/8/2025 | $1,700,000 | $3,400,000 | A burn-focused, product-driven award mechanism intended to provide support for the translation of promising preclinical findings into burn products for clinical application in an austere, resource-limited, distributed operational environment. |
| 2025 Port Infrastructure Development Program | USDOT | 9/10/2025 | $125,000,000 | $500,000,000 | Support efforts by ports and industry stakeholders to improve port and related freight infrastructure to meet the nation’s freight transportation needs and ensure our port infrastructure can meet anticipated growth in freight volumes. Provides funding to ports in both urban and rural areas for planning and capital projects. Includes a statutory set-aside for small ports to continue to improve and expand their capacity to move freight reliably and efficiently and support local and regional economies. Grant updated 5/2/25 and deadline extended from 4/30/25. |
| DoD Rare Cancers, Resource and Community Development Award | DOD | 10/6/2025 | $1,120,000 | $5,600,000 | Supports the development of research resources and clinical or preclinical data sets that will advance the field of rare cancers research and ultimately improve outcomes for individuals with rare cancers. Pre-application due 7/1/25. |
| DOD Amyotrophic Lateral Sclerosis, Therapeutic Development Award | DOD | 8/27/2025 | $1,500,000 | $9,800,000 | Supports research ranging from preclinical validation of therapeutic leads through Food and Drug Administration (FDA) Investigational New Drug (IND)-enabling studies. |
| Alzheimer’s Research Program Transforming Diagnosis Award | DOD | 8/29/2025 | $1,500,000 | $3,200,000 | Supports solutions-oriented research seeking to improve diagnosis and prognosis of Alzheimer’s disease and/or Alzheimer's disease related dementias (AD/ADRD). |
| Alzheimer’s Research Program Transforming Care Award | DOD | 8/29/2025 | $1,800,000 | $5,200,000 | Supports clinical research or clinical trials that provides interventions, innovations, and solutions in critical areas for dementia care for individuals with Alzheimer's disease and Alzheimer's disease related dementias (AD/ADRD) and their care partner(s). |
| DoD Breast Cancer Breakthrough Award Level 3 | DOD | 9/10/2025 | $5,000,000 | $27,900,000 | Supports promising research that has high potential to lead to or make breakthroughs in breast cancer. Small-scale clinical trials are allowed but not required. This funding mechanism allows for a single Principal Investigator (PI), or two partnering PIs referred to as the Initiating PI and the Partnering PI. |
| DOD Ovarian Cancer, Investigator-Initiated Research Award | DOD | 9/11/2025 | $1,200,000 | $8,050,000 | Supports high-impact research that addresses a critical need and has the potential to make an important contribution to ovarian cancer or patient/survivor care. |
| Cyberinfrastructure for Sustained Scientific Innovation | NSF | 12/1/2025 | $20,000,000 | $34,000,000 | Supports flexible, responsive cyberinfrastructure (CI) initiatives with an emphasis on integrated services, measurable outcomes, and community building. Three award types: Elements for small-scale service development, Framework Implementations for interdisciplinary teams addressing shared research challenges, and Transition to Sustainability for sustaining impactful CI projects with long-term plans. |
| Natural Gas Distribution Infrastructure and Safety Modernization Grant | USDOT | $125,000,000 | Funding for a municipality or community owned utility (not including for-profit entities) to repair, rehabilitate, or replace its natural gas distribution pipeline systems or portions thereof, or to acquire equipment to (1) reduce incidents and fatalities and (2) to avoid economic losses. Anticipated to open in Spring/Summer 2026. | ||
| Laboratory Flexible Funding Model (LFFM) | HHS | 1/11/2028 | $1,500,000 | This cooperative agreement is intended to enhance the capacity and capabilities of state human and animal food testing laboratories in support of an integrated food safety system (IFSS). Deadlines: | |
| March 31, 2025, January 12, 2026, January 11, 2027, January 10, 2028. | |||||
| Collaborative Research Using Biosamples and/or Data from Type 1 Diabetes Clinical Studies (R01 - Clinical Trial Not Allowed) | HHS | 3/6/2026 | $1,200,000 | This opportunity is intended to fund investigative teams collaborating to answer important questions about disease mechanisms leading to improved prevention of type 1 diabetes. Deadlines: June 25, 2025 and March 6, 2026. | |
| Development of Medications to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional) | HHS | 8/11/2025 | $3,000,000 | Support the discovery and development of medications to prevent and treat substance use disorders (SUDs) and overdose. The UG3/UH3 Phase Innovation Awards Cooperative Agreement involves 2 phases. The UG3 is to support a project with specific milestones to be accomplished by the end of the 2-year period. The UH3 is to provide funding for 3 years to a project that successfully completed the milestones set in the UG3. | |
| Medications Development for Substance-Use Disorders (U01 Clinical Trial Optional) | HHS | 8/11/2025 | $5,000,000 | Funding to accelerate the development of medication for the treatment of Substance Use Disorders (SUDs) by encouraging research applications to support a diverse array of preclinical and/or clinical research projects. It is expected that these U01s will be short-term (funded for up to 3 years) and large (up to $5 million per year) cooperative agreements with close monitoring and significant scientific involvement of NIDA staff. | |
| Agriculture and Food Research Initiative Competitive Grants Program Foundational and Applied Science Program | USDA | 12/31/2025 | $15,000,000 | $300,000,000 | Funding to advance knowledge in both fundamental and applied sciences important to agriculture. Six priority areas: Plant Health and Production and Plant Products; Animal Health and Production and Animal Products; Food Safety, Nutrition, and Health; Bioenergy, Natural Resources, and Environment; Agriculture Systems and Technology; and Agriculture Economics and Rural Communities. |
| Regional Direct Air Capture Hubs - Recurring Program | DOE | 7/31/2025 | $1,400,000,000 | Deadlines for both Concept Papers and Pre-Applications are due by January 31, 2025. The program seeks to provide flexible and comprehensive pathways to spur the development of commercial DAC facilities, including DAC facilities at mid- to large-scale along with supporting infrastructure, and expand to Regional DAC Hubs. | |
| Carbon Dioxide Transportation Infrastructure Finance and Innovation Future Growth Grants | DOE | 1/2/2026 | $500,000,000 | $500,000,000 | Provides financial assistance for designing, developing, and building CO2 transport systems whose capacity exceeds the CO2 volumes currently under commercial contract. |
| Addressing Barriers to Healthcare Transitions for Survivors of Childhood and Adolescent Cancers (R01 Clinical Trial Optional) | HHS | 10/17/2025 | $1,000,000 | $12,000,000 | Supports multi-level intervention studies that address individual and system level barriers to transitions from pediatric to adult care for survivors of childhood and adolescent cancers. NCI intends to commit $10 million total in FY 2025 and FY 2026 to fund up to 12 awards, across the prior and current issuance of this NOFO. |
| Leveraging Network Infrastructure to Conduct Innovative Research for Women, Children, Pregnant and Lactating Individuals, and Persons with Disabilities (UG3/UH3 - Clinical Trial Optional) | HHS | 11/15/2027 | $6,250,000 | Leverages NICHD clinical research Network infrastructure relevant to infants, children, women, pregnant and lactating individuals, and persons with disabilities to conduct innovative, multisite, investigator-initiated clinical trials and observational studies. | |
| Leveraging Network Infrastructure to Conduct Innovative Research for Women, Children, Pregnant and Lactating Individuals, and Persons with Disabilities (UG3/UH3 - Clinical Trial Optional) | HHS | 11/15/2027 | $6,250,000 | $6,250,000 | Funding to leverage NICHD clinical research Network infrastructure relevant to infants, children, women, pregnant and lactating individuals, and persons with disabilities to conduct innovative, multisite, investigator-initiated clinical trials and observational studies. |
| Alzheimer's Drug-Development Program (U01 Clinical Trial Optional) | HHS | 10/5/2027 | $1,500,000 | Funding support for the pre-clinical and early stage clinical (Phase I) development of novel small-molecule and biologic drug candidates that prevent Alzheimer's disease (AD), slow its progression, or treat its cognitive and behavioral symptoms. | |
| Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed) | HHS | 12/3/2027 | $1,000,000 | $2,000,000 | Invites applications proposing the innovative analysis of existing social science, behavioral, administrative, and neuroimaging data to study the etiology and epidemiology of drug using behaviors and related disorders, prevention of drug use and HIV, and health service utilization. |
| HIV Prevention and Alcohol (R01 Clinical Trials Optional) | HHS | 5/7/2026 | $1,000,000 | $2,000,000 | The NOFO seeks to expand the HIV/AIDS prevention toolkit among alcohol impacted populations with a range of patterns of episodic and long-term use and associated behavioral and biological risks for HIV acquisition. |
| Contraceptive Development Research Centers (P50 Clinical Trial Optional) | HHS | 11/12/2025 | $2,000,000 | $6,000,000 | Funding to support and facilitate multidisciplinary approaches towards the development of new and/or improved contraceptive methods for both men and women through the formation of a Contraceptive Development Research Center. |
| Environmental Health Sciences Core Centers Program (P30 Clinical Trials Optional) | HHS | 1/29/2027 | $1,500,000 | $6,000,000 | Seeking applications for Environmental Health Sciences Core Centers (EHSCC), expected to be the thought leaders for the field and advance the goals of the 2025-2029 NIEHS Strategic Plan. |
| BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed) | HHS | 2/8/2027 | $1,300,000 | $8,000,000 | Seeking applications that will develop and validate novel tools to facilitate the detailed analysis of complex circuits and provide insights into cellular interactions that underlie brain function. |
| BRAIN Initiative: Clinical Studies to Advance Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UH3 Clinical Trial Optional) | HHS | 9/28/2026 | $2,000,000 | $10,000,000 | Funding to encourage investigators to pursue a small clinical trial to obtain critical information necessary to advance recording and/or stimulating devices to treat central nervous system disorders and better understand the human brain (e.g., Early Feasibility Study). |
| BRAIN Initiative: Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UG3/UH3 Clinical Trial Optional) | HHS | 9/28/2026 | $2,000,000 | $10,000,000 | Funding to encourage investigators to pursue translational activities and small clinical studies for recording and/or stimulating devices to treat central nervous system disorders and better understand the human brain. |
| Bidirectional Influences Between Adolescent Social Media Use and Mental Health (R01 Clinical Trial Optional) | HHS | 10/20/2025 | $1,000,000 | $5,000,000 | Seeking applications that focus on understanding bidirectional relationships between social media use and adolescent mental illness, psychiatric symptoms, and risk or resilience for psychopathology, as well as social media as a platform for facilitating the identification of adolescents with or at risk for mental illness, for encouraging appropriate mental health service use, and for delivering preventive and therapeutic interventions. |
| Bidirectional Influences Between Adolescent Social Media Use and Mental Health (R21 Clinical Trial Optional) | HHS | 10/20/2025 | $1,000,000 | $5,000,000 | Seeking applications that focus on understanding bidirectional relationships between social media use and adolescent mental illness, psychiatric symptoms, and risk or resilience for psychopathology, as well as intervention/services research focused on examining the feasibility, acceptability, and preliminary utility of social-media focused interventions and services. |
| High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed) | HHS | 6/1/2027 | $2,000,000 | Seeking applications from groups of NIH-supported investigators to purchase or upgrade a single item of high-end, specialized, commercially available instruments or integrated systems. | |
| Energy Improvements in Rural or Remote Areas – Fiscal Year 2025 Release | DOE | 8/28/2025 | $50,000,000 | $400,000,000 | Supports innovative, community-focused,?clean energy solutions for rural and remote communities of 10,000 people or few. Funding will?help rural and remote communities demonstrate replicable projects, ultimately encouraging widespread adoption and helping to lower energy costs, support local economic development, and enhance energy resiliency. |
| Reissue PAR-21-233 - The Blueprint Neurotherapeutics Network for Biologics (BPN-Biologics) | HHS | 7/15/2027 | $200,000,000 | Provides support for biologic-based therapeutic discovery and development, from lead optimization through phase I clinical testing. | |
| Seeding Critical Advances for Leading Energy technologies with Untapped Potential (SCALEUP) Ready program | DOE | 9/29/2029 | $200,000,000 | Provides a vital mechanism for the support of innovative energy R&D that complements ARPA-E’s primary R&D focus on early-stage transformational energy technologies that still require proof-of-concept. | |
| NOI: Regional Direct Air Capture Hubs – Recurring Program | DOE | $1,300,000,000 | Notice of Intent to Issue Notice of Funding Opportunity: Regional Direct Air Capture Hubs – Recurring Program to support the commercialization of direct air capture (DAC) solutions and the development of four regional DAC hubs. | ||
| Bridge Investment Program - Large Bridge (2026 Funding) | USDOT | 8/1/2025 | Rolling application for Large Bridge Project grants (a project with total eligible costs greater than $100 million) for awards under the Bridge Investment Program (BIP). | ||
| Continuum of Care Competition and Renewal or Replacement of Youth Homeless Demonstration Program Grants | HUD | 8/29/2025 | $15,000,000 | $3,524,000,000 | Designed to promote a community-wide commitment to the goal of ending homelessness; to provide funding for efforts to quickly re-house homeless individuals, families, persons fleeing domestic violence, and youth while minimizing the trauma and dislocation caused by homelessness; to promote access to and effective utilization of mainstream programs by homeless; and to optimize self-sufficiency among those experiencing homelessness. |
| Bridge Investment Program - Planning and Bridge Project Grants (2026 Funding) | USDOT | 10/1/2025 | Rolling application for two funding categories: (1) Planning and (2) Bridge Project grants (a project with total eligible costs not greater than $100 million) for awards under the Bridge Investment Program (BIP). Planning application due 10/1/25 and bridge project application due 11/1/25. | ||
| Notice of Intent to Issue Fiscal Year 2025 Solar Module and Solar Hardware (SMASH) | DOE | 10/10/2025 | Notice of Intent to Fund: The NOFO will seek to address the lack of sufficient private investment that is available to successfully commercialize research and development (R&D) and research, development, and demonstration (RD&D) activities and bring innovative solar photovoltaic (PV) technology to market. | ||
| Accelerated Innovation Deployment (AID) Demonstration | USDOT | 5/26/2026 | $1,000,000 | FY 23-26 grant cycles. Funding to assistance under title 23, U.S.C. in any phase of a highway transportation project between project planning and project delivery, including planning, financing, operation, structures, materials, pavements, environment, and construction | |
| Standardizing Data and Metadata from Wearable Devices | HHS | 6/10/2026 | Supports the creation of standards and related efforts that will allow researchers to easily access data from personal tracking devices. The awardees will be expected to partner with device manufacturers as well as the researcher community. Application budgets are not limited but need to reflect the actual needs of the proposed project. | ||
| REsearch Across Complementary and Integrative Health Institutions (REACH) Virtual Resource Centers | HHS | 8/15/2026 | $850,000 | $2,750,000 | REACH virtual resource centers will foster institutional partnerships and provide resources to support research activities and research training for faculty who work at accredited complementary and integrative health clinical institutions. |
| High Priority HIV and Substance Use Research (R01 Clinical Trial Optional) | HHS | 2/11/2027 | $3,000,000 | Invites innovative research projects with the potential to open new areas of HIV/AIDS research and/or lead to new avenues for prevention, treatment and cure of HIV among people who use drugs (PWUD). | |
| Animal and Veterinary Innovation Centers | HHS | 5/8/2028 | $1,250,000 | $3,000,000 | Soliciting applications for inclusion as Animal and Veterinary Innovation Centers, which are intended to form long-term partnerships to address priority areas for FDA's Center for Veterinary Medicine (CVM). |
| NOI Renewable Integration Management with Innovative High Voltage Direct Current Power Circuit Breakers (REIMAGINE BREAKERS) | DOE | $8,000,000 | Notice of Intent to Fund: Program funding to improve risk assessment and communication for grid operators in the age of big data. | ||
| NOI to Issue Bipartisan Infrastructure Law: Funding Opportunity Announcement No. DE-FOA-0003434 | DOE | Notice of Intent (NOI) to issue an Funding Opportunity Annoucement (FOA) entitled Electric Drive Vehicle Battery Improving Economics, Recovery and Reuse, and State of Health to support research, development, and demonstration of: 1) second-life applications for electric drive vehicle batteries that have been used to power electric drive vehicles; and 2) technologies and processes for final recycling and disposal of the [electric drive vehicle batteries]. | |||
| NOI to release Energy Improvements in Rural or Remote Areas FY24 | DOE | Notice of Intent (NOI) to issue a NOFO entitled “Energy Improvements in Rural or Remote Areas FY24”. The goals are to deliver measurable and sustained benefits to people who live in rural or remote areas; demonstrate rural or remote energy system approaches; and build clean energy knowledge, capacity, and self-reliance in rural and remote parts of America. | |||
| NOI to release Regional Direct Air Capture Hubs – Recurring Program | DOE | Notice of Intent (NOI) to issue a Notice of Funding Opportunity (NOFO) entitled “Regional Direct Air Capture Hubs – Recurring Program” in the fourth quarter of 2024. The goal of this NOFO, along with potential subsequent re-openings and related solicitations (collectively, “the Program”), is to support the commercialization of direct air capture (DAC) solutions and the development of four regional DAC hubs. | |||
| Notice of Intent to Issue FOA number DE-FOA-0003383 entitled Fiscal Year 2024 Vehicle Technologies Office Batteries & Electrification FOA | DOE | Forecasted Opportunity for July/August 2024. The potential funding will drive innovations in low-cost electric vehicle (EV) battery manufacturing, using inexpensive and abundant battery materials in support of a viable domestic materials supply chain, and conducting smart-charge management demonstrations. | |||
| Notice of Intent to Issue: Energy Storage Pilot Demonstrations | DOE | $20,000,000 | $100,000,000 | Anticipated release late summer/early fall. Will support pilot-scale demonstrations for non-lithium, long duration energy storage solutions that advance technical maturity, reduce uncertainty in cost and performance characteristics, generate operational datasets, and increase investor and end-user confidence in technical and commercial maturation pathways and timelines. |
Grant Alerts
Selected Grants & Analysis are below. This a just a representative sample, contact us with your specific needs.
| Grant Name | Agency | Deadline | Award Amounts | Total Funding | Description |
|---|---|---|---|---|---|
| Cooperative Institute Fostering Aquaculture Research and Marketing (CIFARM) | DOC | 9/5/2025 | $300,000,000 | $300,000,000 | Supports the establishment of a Cooperative Institute Fostering Aquaculture Research and Marketing (CIFARM) that will advance key goals in aquaculture, fostering innovation, promote environmental stewardship, and build strong coastal economies; support the robust development of aquaculture in the United States to address the seafood import deficit and benefit the economy; and help the agency fulfill the tenets of the NOAA Aquaculture Strategic Plan. |
| Community College Initiative Program | DOS | 8/4/2025 | $3,937,500 | $3,937,500 | ECA is seeking proposal submissions for one cooperative agreement to design, implement, and oversee the Community College Initiative Program. |
| DoD Toxic Exposures Clinical Trial Partnership Award | DOD | 10/16/2025 | $4,200,000 | $4,200,000 | Funding to support new or existing collaborative partnerships that will rapidly implement clinical trials with the potential to have a significant impact on the prevention, treatment or management of symptoms, diseases, or conditions associated with or resulting from military-related toxic exposures. |
| DoD Toxic Exposures Translational Research Partnership Award | DOD | 10/16/2025 | $2,240,000 | $4,480,000 | Funding to support new or existing collaborative partnerships to pursue translational research that will accelerate the movement of promising ideas in military-related toxic exposure research into clinical applications, including health care products, interventions, technologies, and/or clinical practice guidelines. |
| DHA- Military Health System Research Program | DOD | 10/16/2025 | $1,000,000 | $10,000,000 | Funds innovative and groundbreaking research that examines factors that affect the military health enterprise in terms of economics/cost, quality, outcomes, variation, policies, and the impact to service member readiness. |
| DoD Prostate Cancer, Idea Development Award | DOD | 8/29/2025 | $7,200,000 | $30,500,000 | Supports new ideas that represent innovative approaches to prostate cancer research and have the potential to make an important contribution to the PCRP mission. |
| DoD Prostate Cancer, Clinical Consortium Award | DOD | 8/29/2025 | $7,600,000 | $32,500,000 | Provides support to develop, maintain, and enhance the necessary collaborations and resources to rapidly execute phase 2 and/or phase 2-linked phase 1 (phase1/2) prostate cancer clinical trials. Supports one coordinating center and multiple clinical research sites. |
| DOD Peer Reviewed Cancer, Clinical Trial Award | DOD | 9/25/2025 | $3,000,000 | $33,600,000 | Supports the rapid implementation of clinical trials with the potential to have a significant impact on the treatment or management of cancer within at least one of the FY25 PRCRP topic areas. Clinical trials may be designed to evaluate promising new products, pharmacologic agents (drugs or biologics), devices, clinical guidance, and/or emerging approaches and technologies. Proposed projects may range from small proof-of-concept trials that evaluate the effects of interventions or inform the design of more advanced trials to large-scale trials (up to phase III) to determine efficacy in relevant patient populations. |
| DoD Melanoma, Team Science Award | DOD | 10/1/2025 | $2,400,000 | $16,800,000 | Supports a broad range of hypothesis-driven, multidisciplinary studies that have a short-term goal of advancing the state of the science in melanoma research and/or patient care. |
| DoD Melanoma, Survivorship Research Award | DOD | 10/1/2025 | $1,160,000 | $2,320,000 | Addresses the relatively new and underfunded area of melanoma-specific survivorship by supporting a broad range of innovative and impactful research that has the intended outcome of improving the health and well-being of melanoma survivors, their families, and/or their caregivers. |
| DoD Melanoma, Focused Program Award – Rare Melanomas | DOD | 10/1/2025 | $3,200,000 | $6,400,000 | Supports a multidisciplinary research program of at least two, but not more than three, distinct but complementary research projects addressing an overarching question relevant to rare melanomas. |
| Regional Infrastructure Accelerator Program | USDOT | RIA grants assist entities in developing improved infrastructure priorities and financing strategies for the accelerated development of a project that is eligible for funding under the Transportation Infrastructure Finance and Innovation Act (TIFIA) Credit Program. Next round anticipated in Spring 2026. | |||
| DOD Duchenne Muscular Dystrophy, Clinical/Translational Research Award | DOD | 8/8/2025 | $1,712,000 | $8,560,000 | Supports advanced translational research that will accelerate the movement of promising ideas in Duchenne muscular dystrophy (DMD) research into clinical applications. |
| DoD Military Burn, Patient-Centered Research Award | DOD | 9/8/2025 | $1,700,000 | $3,400,000 | Seeks to bridge the gap between research, practice, and policy by developing a knowledge base that provides clinically useful findings about how interventions, clinical practices, guidelines, tools, and policies can be deployed to burn patients in an austere, resource-limited, distributed operational environment at the point of need. |
| DoD Military Burn, Technology/Therapeutic Development Award | DOD | 9/8/2025 | $1,700,000 | $3,400,000 | A burn-focused, product-driven award mechanism intended to provide support for the translation of promising preclinical findings into burn products for clinical application in an austere, resource-limited, distributed operational environment. |
| 2025 Port Infrastructure Development Program | USDOT | 9/10/2025 | $125,000,000 | $500,000,000 | Support efforts by ports and industry stakeholders to improve port and related freight infrastructure to meet the nation’s freight transportation needs and ensure our port infrastructure can meet anticipated growth in freight volumes. Provides funding to ports in both urban and rural areas for planning and capital projects. Includes a statutory set-aside for small ports to continue to improve and expand their capacity to move freight reliably and efficiently and support local and regional economies. Grant updated 5/2/25 and deadline extended from 4/30/25. |
| DoD Rare Cancers, Resource and Community Development Award | DOD | 10/6/2025 | $1,120,000 | $5,600,000 | Supports the development of research resources and clinical or preclinical data sets that will advance the field of rare cancers research and ultimately improve outcomes for individuals with rare cancers. Pre-application due 7/1/25. |
| DOD Amyotrophic Lateral Sclerosis, Therapeutic Development Award | DOD | 8/27/2025 | $1,500,000 | $9,800,000 | Supports research ranging from preclinical validation of therapeutic leads through Food and Drug Administration (FDA) Investigational New Drug (IND)-enabling studies. |
| Alzheimer’s Research Program Transforming Diagnosis Award | DOD | 8/29/2025 | $1,500,000 | $3,200,000 | Supports solutions-oriented research seeking to improve diagnosis and prognosis of Alzheimer’s disease and/or Alzheimer's disease related dementias (AD/ADRD). |
| Alzheimer’s Research Program Transforming Care Award | DOD | 8/29/2025 | $1,800,000 | $5,200,000 | Supports clinical research or clinical trials that provides interventions, innovations, and solutions in critical areas for dementia care for individuals with Alzheimer's disease and Alzheimer's disease related dementias (AD/ADRD) and their care partner(s). |
| DoD Breast Cancer Breakthrough Award Level 3 | DOD | 9/10/2025 | $5,000,000 | $27,900,000 | Supports promising research that has high potential to lead to or make breakthroughs in breast cancer. Small-scale clinical trials are allowed but not required. This funding mechanism allows for a single Principal Investigator (PI), or two partnering PIs referred to as the Initiating PI and the Partnering PI. |
| DOD Ovarian Cancer, Investigator-Initiated Research Award | DOD | 9/11/2025 | $1,200,000 | $8,050,000 | Supports high-impact research that addresses a critical need and has the potential to make an important contribution to ovarian cancer or patient/survivor care. |
| Cyberinfrastructure for Sustained Scientific Innovation | NSF | 12/1/2025 | $20,000,000 | $34,000,000 | Supports flexible, responsive cyberinfrastructure (CI) initiatives with an emphasis on integrated services, measurable outcomes, and community building. Three award types: Elements for small-scale service development, Framework Implementations for interdisciplinary teams addressing shared research challenges, and Transition to Sustainability for sustaining impactful CI projects with long-term plans. |
| Natural Gas Distribution Infrastructure and Safety Modernization Grant | USDOT | $125,000,000 | Funding for a municipality or community owned utility (not including for-profit entities) to repair, rehabilitate, or replace its natural gas distribution pipeline systems or portions thereof, or to acquire equipment to (1) reduce incidents and fatalities and (2) to avoid economic losses. Anticipated to open in Spring/Summer 2026. | ||
| Laboratory Flexible Funding Model (LFFM) | HHS | 1/11/2028 | $1,500,000 | This cooperative agreement is intended to enhance the capacity and capabilities of state human and animal food testing laboratories in support of an integrated food safety system (IFSS). Deadlines: | |
| March 31, 2025, January 12, 2026, January 11, 2027, January 10, 2028. | |||||
| Collaborative Research Using Biosamples and/or Data from Type 1 Diabetes Clinical Studies (R01 - Clinical Trial Not Allowed) | HHS | 3/6/2026 | $1,200,000 | This opportunity is intended to fund investigative teams collaborating to answer important questions about disease mechanisms leading to improved prevention of type 1 diabetes. Deadlines: June 25, 2025 and March 6, 2026. | |
| Development of Medications to Prevent and Treat Substance Use Disorders and Overdose (UG3/UH3 - Clinical Trial Optional) | HHS | 8/11/2025 | $3,000,000 | Support the discovery and development of medications to prevent and treat substance use disorders (SUDs) and overdose. The UG3/UH3 Phase Innovation Awards Cooperative Agreement involves 2 phases. The UG3 is to support a project with specific milestones to be accomplished by the end of the 2-year period. The UH3 is to provide funding for 3 years to a project that successfully completed the milestones set in the UG3. | |
| Medications Development for Substance-Use Disorders (U01 Clinical Trial Optional) | HHS | 8/11/2025 | $5,000,000 | Funding to accelerate the development of medication for the treatment of Substance Use Disorders (SUDs) by encouraging research applications to support a diverse array of preclinical and/or clinical research projects. It is expected that these U01s will be short-term (funded for up to 3 years) and large (up to $5 million per year) cooperative agreements with close monitoring and significant scientific involvement of NIDA staff. | |
| Agriculture and Food Research Initiative Competitive Grants Program Foundational and Applied Science Program | USDA | 12/31/2025 | $15,000,000 | $300,000,000 | Funding to advance knowledge in both fundamental and applied sciences important to agriculture. Six priority areas: Plant Health and Production and Plant Products; Animal Health and Production and Animal Products; Food Safety, Nutrition, and Health; Bioenergy, Natural Resources, and Environment; Agriculture Systems and Technology; and Agriculture Economics and Rural Communities. |
| Regional Direct Air Capture Hubs - Recurring Program | DOE | 7/31/2025 | $1,400,000,000 | Deadlines for both Concept Papers and Pre-Applications are due by January 31, 2025. The program seeks to provide flexible and comprehensive pathways to spur the development of commercial DAC facilities, including DAC facilities at mid- to large-scale along with supporting infrastructure, and expand to Regional DAC Hubs. | |
| Carbon Dioxide Transportation Infrastructure Finance and Innovation Future Growth Grants | DOE | 1/2/2026 | $500,000,000 | $500,000,000 | Provides financial assistance for designing, developing, and building CO2 transport systems whose capacity exceeds the CO2 volumes currently under commercial contract. |
| Addressing Barriers to Healthcare Transitions for Survivors of Childhood and Adolescent Cancers (R01 Clinical Trial Optional) | HHS | 10/17/2025 | $1,000,000 | $12,000,000 | Supports multi-level intervention studies that address individual and system level barriers to transitions from pediatric to adult care for survivors of childhood and adolescent cancers. NCI intends to commit $10 million total in FY 2025 and FY 2026 to fund up to 12 awards, across the prior and current issuance of this NOFO. |
| Leveraging Network Infrastructure to Conduct Innovative Research for Women, Children, Pregnant and Lactating Individuals, and Persons with Disabilities (UG3/UH3 - Clinical Trial Optional) | HHS | 11/15/2027 | $6,250,000 | Leverages NICHD clinical research Network infrastructure relevant to infants, children, women, pregnant and lactating individuals, and persons with disabilities to conduct innovative, multisite, investigator-initiated clinical trials and observational studies. | |
| Leveraging Network Infrastructure to Conduct Innovative Research for Women, Children, Pregnant and Lactating Individuals, and Persons with Disabilities (UG3/UH3 - Clinical Trial Optional) | HHS | 11/15/2027 | $6,250,000 | $6,250,000 | Funding to leverage NICHD clinical research Network infrastructure relevant to infants, children, women, pregnant and lactating individuals, and persons with disabilities to conduct innovative, multisite, investigator-initiated clinical trials and observational studies. |
| Alzheimer's Drug-Development Program (U01 Clinical Trial Optional) | HHS | 10/5/2027 | $1,500,000 | Funding support for the pre-clinical and early stage clinical (Phase I) development of novel small-molecule and biologic drug candidates that prevent Alzheimer's disease (AD), slow its progression, or treat its cognitive and behavioral symptoms. | |
| Accelerating the Pace of Substance Use Research Using Existing Data (R01 Clinical Trial Not Allowed) | HHS | 12/3/2027 | $1,000,000 | $2,000,000 | Invites applications proposing the innovative analysis of existing social science, behavioral, administrative, and neuroimaging data to study the etiology and epidemiology of drug using behaviors and related disorders, prevention of drug use and HIV, and health service utilization. |
| HIV Prevention and Alcohol (R01 Clinical Trials Optional) | HHS | 5/7/2026 | $1,000,000 | $2,000,000 | The NOFO seeks to expand the HIV/AIDS prevention toolkit among alcohol impacted populations with a range of patterns of episodic and long-term use and associated behavioral and biological risks for HIV acquisition. |
| Contraceptive Development Research Centers (P50 Clinical Trial Optional) | HHS | 11/12/2025 | $2,000,000 | $6,000,000 | Funding to support and facilitate multidisciplinary approaches towards the development of new and/or improved contraceptive methods for both men and women through the formation of a Contraceptive Development Research Center. |
| Environmental Health Sciences Core Centers Program (P30 Clinical Trials Optional) | HHS | 1/29/2027 | $1,500,000 | $6,000,000 | Seeking applications for Environmental Health Sciences Core Centers (EHSCC), expected to be the thought leaders for the field and advance the goals of the 2025-2029 NIEHS Strategic Plan. |
| BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed) | HHS | 2/8/2027 | $1,300,000 | $8,000,000 | Seeking applications that will develop and validate novel tools to facilitate the detailed analysis of complex circuits and provide insights into cellular interactions that underlie brain function. |
| BRAIN Initiative: Clinical Studies to Advance Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UH3 Clinical Trial Optional) | HHS | 9/28/2026 | $2,000,000 | $10,000,000 | Funding to encourage investigators to pursue a small clinical trial to obtain critical information necessary to advance recording and/or stimulating devices to treat central nervous system disorders and better understand the human brain (e.g., Early Feasibility Study). |
| BRAIN Initiative: Next-Generation Devices for Recording and Modulation in the Human Central Nervous System (UG3/UH3 Clinical Trial Optional) | HHS | 9/28/2026 | $2,000,000 | $10,000,000 | Funding to encourage investigators to pursue translational activities and small clinical studies for recording and/or stimulating devices to treat central nervous system disorders and better understand the human brain. |
| Bidirectional Influences Between Adolescent Social Media Use and Mental Health (R01 Clinical Trial Optional) | HHS | 10/20/2025 | $1,000,000 | $5,000,000 | Seeking applications that focus on understanding bidirectional relationships between social media use and adolescent mental illness, psychiatric symptoms, and risk or resilience for psychopathology, as well as social media as a platform for facilitating the identification of adolescents with or at risk for mental illness, for encouraging appropriate mental health service use, and for delivering preventive and therapeutic interventions. |
| Bidirectional Influences Between Adolescent Social Media Use and Mental Health (R21 Clinical Trial Optional) | HHS | 10/20/2025 | $1,000,000 | $5,000,000 | Seeking applications that focus on understanding bidirectional relationships between social media use and adolescent mental illness, psychiatric symptoms, and risk or resilience for psychopathology, as well as intervention/services research focused on examining the feasibility, acceptability, and preliminary utility of social-media focused interventions and services. |
| High-End Instrumentation (HEI) Grant Program (S10 Clinical Trial Not Allowed) | HHS | 6/1/2027 | $2,000,000 | Seeking applications from groups of NIH-supported investigators to purchase or upgrade a single item of high-end, specialized, commercially available instruments or integrated systems. | |
| Energy Improvements in Rural or Remote Areas – Fiscal Year 2025 Release | DOE | 8/28/2025 | $50,000,000 | $400,000,000 | Supports innovative, community-focused,?clean energy solutions for rural and remote communities of 10,000 people or few. Funding will?help rural and remote communities demonstrate replicable projects, ultimately encouraging widespread adoption and helping to lower energy costs, support local economic development, and enhance energy resiliency. |
| Reissue PAR-21-233 - The Blueprint Neurotherapeutics Network for Biologics (BPN-Biologics) | HHS | 7/15/2027 | $200,000,000 | Provides support for biologic-based therapeutic discovery and development, from lead optimization through phase I clinical testing. | |
| Seeding Critical Advances for Leading Energy technologies with Untapped Potential (SCALEUP) Ready program | DOE | 9/29/2029 | $200,000,000 | Provides a vital mechanism for the support of innovative energy R&D that complements ARPA-E’s primary R&D focus on early-stage transformational energy technologies that still require proof-of-concept. | |
| NOI: Regional Direct Air Capture Hubs – Recurring Program | DOE | $1,300,000,000 | Notice of Intent to Issue Notice of Funding Opportunity: Regional Direct Air Capture Hubs – Recurring Program to support the commercialization of direct air capture (DAC) solutions and the development of four regional DAC hubs. | ||
| Bridge Investment Program - Large Bridge (2026 Funding) | USDOT | 8/1/2025 | Rolling application for Large Bridge Project grants (a project with total eligible costs greater than $100 million) for awards under the Bridge Investment Program (BIP). | ||
| Continuum of Care Competition and Renewal or Replacement of Youth Homeless Demonstration Program Grants | HUD | 8/29/2025 | $15,000,000 | $3,524,000,000 | Designed to promote a community-wide commitment to the goal of ending homelessness; to provide funding for efforts to quickly re-house homeless individuals, families, persons fleeing domestic violence, and youth while minimizing the trauma and dislocation caused by homelessness; to promote access to and effective utilization of mainstream programs by homeless; and to optimize self-sufficiency among those experiencing homelessness. |
| Bridge Investment Program - Planning and Bridge Project Grants (2026 Funding) | USDOT | 10/1/2025 | Rolling application for two funding categories: (1) Planning and (2) Bridge Project grants (a project with total eligible costs not greater than $100 million) for awards under the Bridge Investment Program (BIP). Planning application due 10/1/25 and bridge project application due 11/1/25. | ||
| Notice of Intent to Issue Fiscal Year 2025 Solar Module and Solar Hardware (SMASH) | DOE | 10/10/2025 | Notice of Intent to Fund: The NOFO will seek to address the lack of sufficient private investment that is available to successfully commercialize research and development (R&D) and research, development, and demonstration (RD&D) activities and bring innovative solar photovoltaic (PV) technology to market. | ||
| Accelerated Innovation Deployment (AID) Demonstration | USDOT | 5/26/2026 | $1,000,000 | FY 23-26 grant cycles. Funding to assistance under title 23, U.S.C. in any phase of a highway transportation project between project planning and project delivery, including planning, financing, operation, structures, materials, pavements, environment, and construction | |
| Standardizing Data and Metadata from Wearable Devices | HHS | 6/10/2026 | Supports the creation of standards and related efforts that will allow researchers to easily access data from personal tracking devices. The awardees will be expected to partner with device manufacturers as well as the researcher community. Application budgets are not limited but need to reflect the actual needs of the proposed project. | ||
| REsearch Across Complementary and Integrative Health Institutions (REACH) Virtual Resource Centers | HHS | 8/15/2026 | $850,000 | $2,750,000 | REACH virtual resource centers will foster institutional partnerships and provide resources to support research activities and research training for faculty who work at accredited complementary and integrative health clinical institutions. |
| High Priority HIV and Substance Use Research (R01 Clinical Trial Optional) | HHS | 2/11/2027 | $3,000,000 | Invites innovative research projects with the potential to open new areas of HIV/AIDS research and/or lead to new avenues for prevention, treatment and cure of HIV among people who use drugs (PWUD). | |
| Animal and Veterinary Innovation Centers | HHS | 5/8/2028 | $1,250,000 | $3,000,000 | Soliciting applications for inclusion as Animal and Veterinary Innovation Centers, which are intended to form long-term partnerships to address priority areas for FDA's Center for Veterinary Medicine (CVM). |
| NOI Renewable Integration Management with Innovative High Voltage Direct Current Power Circuit Breakers (REIMAGINE BREAKERS) | DOE | $8,000,000 | Notice of Intent to Fund: Program funding to improve risk assessment and communication for grid operators in the age of big data. | ||
| NOI to Issue Bipartisan Infrastructure Law: Funding Opportunity Announcement No. DE-FOA-0003434 | DOE | Notice of Intent (NOI) to issue an Funding Opportunity Annoucement (FOA) entitled Electric Drive Vehicle Battery Improving Economics, Recovery and Reuse, and State of Health to support research, development, and demonstration of: 1) second-life applications for electric drive vehicle batteries that have been used to power electric drive vehicles; and 2) technologies and processes for final recycling and disposal of the [electric drive vehicle batteries]. | |||
| NOI to release Energy Improvements in Rural or Remote Areas FY24 | DOE | Notice of Intent (NOI) to issue a NOFO entitled “Energy Improvements in Rural or Remote Areas FY24”. The goals are to deliver measurable and sustained benefits to people who live in rural or remote areas; demonstrate rural or remote energy system approaches; and build clean energy knowledge, capacity, and self-reliance in rural and remote parts of America. | |||
| NOI to release Regional Direct Air Capture Hubs – Recurring Program | DOE | Notice of Intent (NOI) to issue a Notice of Funding Opportunity (NOFO) entitled “Regional Direct Air Capture Hubs – Recurring Program” in the fourth quarter of 2024. The goal of this NOFO, along with potential subsequent re-openings and related solicitations (collectively, “the Program”), is to support the commercialization of direct air capture (DAC) solutions and the development of four regional DAC hubs. | |||
| Notice of Intent to Issue FOA number DE-FOA-0003383 entitled Fiscal Year 2024 Vehicle Technologies Office Batteries & Electrification FOA | DOE | Forecasted Opportunity for July/August 2024. The potential funding will drive innovations in low-cost electric vehicle (EV) battery manufacturing, using inexpensive and abundant battery materials in support of a viable domestic materials supply chain, and conducting smart-charge management demonstrations. | |||
| Notice of Intent to Issue: Energy Storage Pilot Demonstrations | DOE | $20,000,000 | $100,000,000 | Anticipated release late summer/early fall. Will support pilot-scale demonstrations for non-lithium, long duration energy storage solutions that advance technical maturity, reduce uncertainty in cost and performance characteristics, generate operational datasets, and increase investor and end-user confidence in technical and commercial maturation pathways and timelines. |
